ncRNA name | Dusp14 siRNA |
ncRNA Category | siRNA |
Disease name | optic nerve injury |
Species | Rattus norvegicus |
Tissues/Cell_line | retinal ganglion cells (RGCs) |
Methods | microarray, siRNA transfection, immunohistochemistry, qRT-PCR, Western blot |
Expression pattern | associated |
Functional description | Decreasing Dusp14 expression or disrupting its function in RGCs increased axon growth in vitro and promoted survival and optic nerve regeneration after optic nerve injury in vivo. |
PubMed ID | 29860460 |
Year | 2018 |
Title | The Krüppel-Like Factor Gene Target Dusp14 Regulates Axon Growth and Regeneration. |
Drug-related ncRNA | NO |
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